Martin Pleasance Tissue Salts Comb D Skin Disorders 250T. For minor skin ailments, scalp eruptions, eczema, acne, scaling of the skin and allied conditions. When you want a natural remedy for skin troubles, Combination D is an effective combination of the 4 minerals needed by the body for healthy skin and maintenance. It is best taken as a course of treatment. Tissue Salts are micro doses of minerals that help rectify mineral imbalances which may be the cause of many common ailments. Tissue Salts may assist the absorption of nutrients from food and supplements. This combination of Schuessler Tissue Salts, in an easy to digest tablet, provides relief from skin disorders such as acne and eczema.