Garcinia mangostana aka Mangosteen.

Mangosteen fruit, and particularly its pericarp, is exceptionally rich in xanthones—such as α , β , and γ mangostin. These polyphenolic compounds are documented to exhibit broad-spectrum antioxidant activity, arresting oxidative damage at the mitochondrial level and modulating NF κB signaling pathways to reduce inflammation.

Preclinical research demonstrates that α mangostin downregulates pro-inflammatory cytokines (e.g., TNF α, IL 6), and inhibits COX 2 and iNOS expression, supporting anti-inflammatory and analgesic effects. Additionally, it manifests antibacterial and antifungal properties against pathogens like Staphylococcus aureus and Candida albicans, reinforcing immune defense.

In metabolic research, mangostin derivatives have been shown to aid weight management by inhibiting adipogenesis and supporting lipid metabolism. They also improve insulin sensitivity in murine models through enhanced GLUT4 translocation.
Emerging neuroprotective evidence suggests mangosteen xanthones inhibit Aβ aggregation and reduce neuroinflammation, indicating potential therapeutic value in neurodegenerative disease models. Our Mangosteen tincture delivers concentrated xanthone bioactives, ideal for individuals targeting inflammation control, metabolic balance, and cognitive protection.